The Presbytery is composed of twenty-nine worshiping communities in seven counties of eastern Pennsylvania: Luzerne, Monroe, Carbon, Schuylkill, Northampton, Lehigh, and Berks. It includes two Arabic fellowships, the Korean Church of the Lehigh Valley, a new church development, The Barn; and a new worshiping community, Blank Slate. It is one of seventeen regional bodies that make up the Synod of the Trinity.
The Lehigh Presbytery office is located in the First Presbyterian Church of Allentown.